DR is a serious eye-disease caused by diabetes that can lead to vision impairment and blindness if it is not detected and treated early enough. The WHO estimates that there are over 422 million people with diabetes worldwide. Of these 35% or over 148 million are estimated to have DR with potential for vision impairment and 11% or 48 million are estimated to have Vision Threating DR that can lead to blindness. Prevention of vision loss requires early detection of DR via regular eye exams and screening by a trained ophthalmologist or eye care professional. However, given the large numbers of people affected worldwide, there are not sufficient specialists globally to screen everyone at risk. The shortfall is particularly acute in developing countries, including India, and many countries in Asia and Africa. In addition, many affected people live in remote areas with little or no access to clinics and screening facilities. This makes Diabetic Retinopathy a global healthcare challenge that needs urgent resolution.